Blogs
The Acoustic GFP: How Gas …
The Acoustic GFP: How Gas Vesicles Are Giving Ultrasound a Reporter Gene
Before 1994, if you wanted to study gene expression in a specific cell type, you first had to kill it. Standard methods (antibody staining, in situ hybridization, beta-galactosidase assays) all required fixing and …
Rewriting the Code: A …
Rewriting the Code: A Decade of Genome Editing and Where It’s Heading
In 1949, Linus Pauling published a paper showing that sickle cell disease was caused by a single abnormal protein in red blood cells. He called it a “molecular disease,” the first time a human illness had been …
The $3 Billion Blueprint: …
The $3 Billion Blueprint: How We Sequenced the Human Genome and Why the Hard Part Is Still Ahead
In 2000, sequencing a single human genome cost approximately $100 million and took years of coordinated effort across dozens of institutions on multiple continents. Today it costs roughly $200 and takes …